Feed-grade Zinc Oxide ZnO Used to Control Diarrhea in Piglets
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The World Bank expects global economic growth to slow significantly, from 5.5% in 2021 to 4.1% in 2022 and further to 3.2% in 2023. Growth in East Asia and the Pacific is expected to slow to 5.1 percent in 2022, reflecting the impact of China's economic slowdown, the report said. China's economic growth is expected to fall to 5.1% in 2022, close to potential growth, due to the ongoing impact of the COVID-19 pandemic and the Chinese government's tightening of regulations in certain sectors of the economy. The report said that the rapid spread of the Omicron variant means that the new crown epidemic is likely to continue to disrupt economic activity in the near future. In addition, decelerating growth in major economies, including the United States and China, will depress external demand in emerging markets and developing economies.
Slow economic growth has a huge impact on zinc oxide.
Zinc oxide is an oxide of zinc. Insoluble in water, soluble in acids and strong bases. Zinc oxide is mainly used in chemical industry, pharmaceutical industry, agriculture and other fields.
Feed-grade zinc oxide has a significant effect on the safe control of piglet diarrhea. However, zinc oxide will also cause rough coat of piglets, unbalanced absorption of trace elements, late growth retardation, environmental pollution and other problems. Therefore, feed-grade zinc oxide is a double-edged sword in controlling diarrhea in piglets.
Zinc oxide does have a good effect on controlling diarrhea. But zinc oxide as an amphoteric oxide, first of all, more than 70% of zinc oxide in gastric acid can not pass safely in the form of functional molecular state ZnO, and is transformed into Zn2+ which has no diarrhea control effect. Not to mention the destruction of bile and small intestinal fluid in the intestine. This is an important reason why a large amount of zinc oxide must be added to ensure that enough ZnO reaches the intestinal tract to play a role and achieve a good diarrhea control effect. For those dissolved Zn2+, will be over-absorbed, high blood zinc concentration, resulting in adverse effects on piglet coat color, growth speed and immune function.
So how to maximize the efficacy of zinc oxide, let the zinc of 1500ppm (based on zinc) play the role and effect of 3000ppm under conventional conditions, so that zinc oxide is not destroyed by digestive juices such as gastric acid, and exists and evenly dispersed in the intestinal tract in the form of molecular ZnO in its effective form?
How to deal with it?
Acid resistance, compatibility with chyme and lipophilicity are the decisive factors that determine whether zinc oxide can maximize the effect of antidiarrheal convergence. Only when zinc oxide is acid-resistant, can it not be neutralized by gastric acid, and can it reach the intestinal tract with molecular zinc oxide particles that can control diarrhea; only when zinc oxide is compatible with chyme can it be rapidly and uniformly dispersed in the intestinal tract and form a uniform protective film on the surface of the entire intestinal mucosa; only when zinc oxide is lipophilic, it can be in close contact with the intestinal mucosa of lipids and enrich to the surface of the intestinal mucosa, and the effect will be better.
How to treat zinc oxide with acid resistance? How to make zinc oxide disperse evenly in the intestines? How to make zinc oxide in close contact with intestinal mucosa? It is a problem that the manufacturer needs to solve.
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The Free Trade Agreement between India and the United Arab Emirates (UAE) has come into force on.
The UAE is the gateway to the Middle East, North Africa, Central Asia, and sub-Saharan Africa, said Subramaniam, a senior official at India's Ministry of Commerce and Industry. The agreement will help boost bilateral trade in goods from $60 billion a year now to $100 billion a year within five years.
On 18 February 2022, India and the United Arab Emirates signed the Comprehensive Economic Partnership Agreement. With the entry into force of the agreement, 90 percent of Indian goods and 65 percent of UAE goods will enjoy tariff-free market access.
Apart from its FTA with the UAE, India is also pursuing FTAs with Australia, the UK, Canada, Israel, the European Union, and the Gulf Cooperation Council.
Influenced by international situations, the supply and prices of many zinc oxide are still very uncertain.